Comfortable Sleep Apnea Treatment

Genio treats your obstructive sleep apnea while you and your partner enjoy restful and comfortable nights.

What Is Genio?

Genio is a treatment for obstructive sleep apnea (OSA).

The Genio system consists of a neurostimulator, an activation chip, a charging unit and adhesive patches.

The tiny neurostimulator is implanted under the chin. Its electrodes are put in contact with both branches of the hypoglossal nerve resulting in bilateral stimulation of the nerve.

The neurostimulator is driven by an external activation chip that is attached under the chin at night with an adhesive patch.

During sleep, stimulation triggers a small forward movement of the back of the tongue, preventing it from falling back and blocking the upper airway.

What Makes Genio Different?

  • Discreet Neurostimulator
    Implantation of the Genio neurostimulator requires only a discreet incision under the chin and a short hospital stay.
  • Safe by Design
    No batteries, sensors or leads inside the body. No surgery required to replace system components. No evidence of system parts under your skin.
  • MRI Compatible
    Genio is compatible with full-body MRI scans.
  • Tailored to Your Needs
    Because Genio's wearable is external, the system can be easily customized and upgraded, allowing you to benefit from the latest advances in stimulation and comfort without further surgery.

The Genio System

Watch a short video animation that explains how the Genio system works.

Watch the video

How Does Genio Work?

Genio uses hypoglossal nerve stimulation (HGNS) to treat obstructive sleep apnea.
This therapy works via direct neurostimulation of the hypoglossal nerve during sleep, which activates the genioglossus muscle, causing the tongue to protrude forward.

The effectiveness of Genio and hypoglossal nerve stimulation in treating obstructive sleep apnea has been scientifically proven in patients with moderate to severe obstructive sleep apnea.

Data demonstrate that treatment with the Genio system was safe and effective, and resulted in significant improvement in patients’ quality of life.

  • Improvement in the severity of sleep apnea
  • Positive impact on snoring
  • Easy to use and comfortable

Thanks to Genio, you and your bed partner may finally enjoy restful nights, without noise and without the discomfort of a mask.

Hypoglossal nerve stimulation will be very important in the future for patients with OSA as alternative for PAP incompliance or non-adherence.

Prof. Dr. med. Clemens Heiser
Prof. Dr. med. Clemens Heiser, sleep physician, Head of the sleep medicine center of the Clinic for ear, nose and throat medicine, TU Munich, Germany

How to Use Genio?

  1. During the Day
    You charge the activation chip using the charging unit.
  2. Before Going to Bed
    You connect the activation chip to a new adhesive patch and attach it under your chin.
  3. When You Sleep
    The stimulation starts when you fall asleep. Your breathing frequency is used as a reference to adjust the stimulation cycle to ensure you enjoy a good sleep.
  4. When You Wake Up
    You detach the adhesive patch and disconnect the activation chip. Then, you plug the activation chip to the charging unit. It will be fully charged in a few hours.

The Genio Routine

Genio is easy to use and allows you to treat your sleep apnea more comfortably.

Watch the video

Genio User Stories

What to Do if CPAP Does Not Work?

Genio therapy is indicated for patients who cannot tolerate or have failed CPAP therapy.

Answer a few questions to find out if Genio is right for you.

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© 2025 Nyxoah. All rights reserved.
Genio is a registered trademark of Nyxoah.

The Genio system is CE-marked as a medical device.